Government study comparing finasteride, dutasteride and placebo
https://healthell.blogspot.com/2018/08/government-study-comparing-finasteride.html
https://clinicaltrials.gov/ct2/show/results/NCT01231607?show_locs=Y§=X430125&view=results#othr
ClinicalTrials.gov Identifier: NCT01231607 |
Recruitment Status: Completed
First Posted: November 1, 2010
Results First Posted: October 4, 2012
Last Update Posted: August 10, 2018
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Sponsor: GlaxoSmithKline
Dutasteride 0.02 mg | Dutasteride 0.1 mg | Dutasteride 0.5 mg | Finasteride 1 mg | Placebo | |
---|---|---|---|---|---|
Total, Other (not including serious) Adverse Events | |||||
# participants affected / at risk | 34/185 (18.38%) | 34/188 (18.09%) | 41/184 (22.28%) | 32/179 (17.88%) | 36/181 (19.89%) |
Infections and infestations | |||||
Nasopharyngitis † | |||||
# participants affected / at risk | 19/185 (10.27%) | 15/188 (7.98%) | 23/184 (12.50%) | 14/179 (7.82%) | 16/181 (8.84%) |
Nervous system disorders | |||||
Headache † | |||||
# participants affected / at risk | 8/185 (4.32%) | 8/188 (4.26%) | 11/184 (5.98%) | 5/179 (2.79%) | 16/181 (8.84%) |
Psychiatric disorders | |||||
Libido decreased † | |||||
# participants affected / at risk | 10/185 (5.41%) | 9/188 (4.79%) | 6/184 (3.26%) | 9/179 (5.03%) | 2/181 (1.10%) |
Reproductive system and breast disorders | |||||
Erectile dysfunction † | |||||
# participants affected / at risk | 8/185 (4.32%) | 7/188 (3.72%) | 10/184 (5.43%) | 10/179 (5.59%) | 7/181 (3.87%) |
Limitations of the study, such as early termination leading to small numbers of participants analyzed and technical problems with measurement leading to unreliable or uninterpretable data
Dr. Rassman’s Comment: I want to call you attention to the chart here which discusses sexual side effects between these medications and the placebo. To find out the incidence of the Libido problems and Erectile Dysfunction from this study you must subtract the placebo numbers. If this is true, the incidence is relatively low.
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